Cancer Diagnosis Program | Biorepositories and Biospecimen Research Branch

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Stability of carboxyhemoglobin in stored and mailed blood samples.

Author(s): Hampson NB

Publication: Am J Emerg Med, 2008, Vol. 26, Page 191-5

PubMed ID: 18272101 PubMed Review Paper? No

Purpose of Paper

Conclusion of Paper

Studies

1. Study Purpose

   The purpose of this study was to determine the effects of storage duration at room temperature and 4 degrees C and mailing at ambient temperatures on levels of COHb in blood specimens. 20 tubes of sodium heparin anticoagulated blood from a single individual were mixed with carbon monoxide in nitrogen to obtain 25-35% CoHb. Blood was then transferred to tubes without additive for storage at room temperature or 4 degrees C.

   Summary of Findings:

   COHb levels were unaffected by up to 28 days of storage at 4 degrees C or room temperature. Shipping specimens at ambient temperatures had no effects on COHb levels.

   Biospecimens

   • Bodily Fluid - Blood

   Preservative Types

   • None (Fresh)

   Diagnoses:

   • Not specified

   Platform:

   Analyte	Technology Platform
   Protein	Clinical chemistry/auto analyzer

   Pre-analytical Factors:

   Classification	Pre-analytical Factor	Value(s)
   Storage	Storage temperature	4 degrees C Room temperature
   Storage	Storage duration	0 days 1 day 2 days 3 days 4 days 5 days 6 days 7 days 14 days 21 days 28 days
   Storage	Between site transportation method	Mailed Not transported
   Storage	Specimen transport duration/condition	Within Seattle Round trip between Washington and Indiana Round trip between Washington and Florida

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